YOUR GUIDE TO PEPTIDES
My Story
When I went on full HRT, I expected to feel like myself again - and don’t get me wrong, it helped tremendously. But the truth is that my body was still holding on to inflammation that made me feel puffy, sluggish, and just… not at home in my skin. That’s when I decided to layer in a microdose of glp1/gip/b12.
My intent was not weight-loss, or some a magic fix, but a tool to calm the constant tug-of-war my hormones were having with my metabolism.
The difference has been night and day. Within weeks, I dropped 8 pounds - not of “diet” weight, but of pure inflammation. My face looks less swollen, my midsection had definition again, and I finally feel aligned with the work I’ve been putting into my health. Pairing microdosed glp1 with HRT hasn’t just been about the scale - it’s been about unlocking a version of myself that feels clear, strong, and back in control.
GLP1 & GLP1/GIP
HOW DO THEY WORK?
Let's explore what a GLP-1 peptide is and how it functions. GLP-1 works by mimicking the natural hormone called glucagon-like peptide-1 (GLP-1) that your body produces in response to eating. GLP-1 plays an essential role in regulating blood sugar, appetite, and digestion.
1. Slowing Down Digestion GLP-1 peptides slow the emptying of your stomach, which helps you feel full longer. This not only reduces the amount you eat but also helps stabilize blood sugar levels after meals.
2. Reducing Appetite. They work on areas of the brain that control hunger, specifically the hypothalamus, to suppress your appetite. This makes it easier to eat less without feeling deprived.
3. Supporting Blood Sugar Control GLP-1 peptides enhance insulin production (when blood sugar is high) and reduce the release of glucagon (a hormone that raises blood sugar). This helps keep blood sugar levels stable, which is especially beneficial for people with type 2 diabetes.
4. Promoting Fat Loss By reducing calorie intake and improving metabolic efficiency, GLP-1 peptides can help the body burn fat more effectively while preserving lean muscle mass.
WHAT'S THE DIFFERENCE BETWEEN TIRZEPATIDE & SEMAGLUTIDE?
Both Tirzepatide and Semaglutide are medications that belong to a class known as GLP-1 receptor agonists, primarily used for weight loss and metabolic health.
Here’s a breakdown of the differences between the two, especially from a weight loss perspective, and how Tirzepatide may specifically help the brain.
Key Differences:
1. Semaglutide: Works by activating GLP-1 receptors, which help regulate appetite and food intake, leading to reduced hunger and increased feelings of fullness. This results in lower calorie consumption.
-Tirzepatide: In addition to activating GLP-1 receptors, Tirzepatide also targets GIP (Gastric Inhibitory Polypeptide) receptors. This dual-action mechanism may offer enhanced weight loss effects by more effectively regulating appetite and metabolism compared to Semaglutide alone.
2. Weight Loss Outcomes: - While both medications are effective for weight loss, studies suggest that Tirzepatide may lead to greater weight loss in individuals by 30%. The combination of the GLP-1 and GIP pathways can potentially drive higher reductions in body weight and better metabolic changes.
3. Dosing and Administration: - Both medications are typically administered via injection, but the dosing schedules and specific recommendations may vary, with Tirzepatide often showing flexibility in dosing based on individual patient response. ​
Tirzepatide and Brain Health
Tirzepatide may also have particular benefits for the brain, which can further support weight loss and overall well-being:
1. Appetite Regulation: By affecting hormones that regulate hunger and satiety, Tirzepatide can help reduce cravings and emotional eating. This improved appetite control may lead to a more mindful approach to eating.
2. Cognitive Function and Mood: Some research suggests that GLP-1 agonists may exert neuroprotective effects. Tirzepatide’s action on both GLP-1 and GIP receptors can potentially influence brain functions related to mood and cognition. For instance, better appetite control and reduced fluctuations in blood sugar levels can lead to improved mood and energy levels, positively impacting mental health.
3. Reducing Inflammation: Weight loss, particularly through medications like Tirzepatide, can help reduce inflammation in the body—including in the brain. Chronic inflammation is linked to various neurological issues, and reducing it may support cognitive health over time.
While both Tirzepatide and Semaglutide are effective for weight loss, Tirzepatide’s dual-action mechanism may provide enhanced results. Additionally, Tirzepatide’s potential benefits for the brain, especially around appetite regulation and inflammation reduction, can further enhance overall well-being during a weight loss journey.
Both medications represent promising options for individuals looking to improve their health and achieve sustainable weight loss, especially when combined with a supportive lifestyle.
GLP-1 USERS: BEFORE & AFTER
NAD+
Boosted Energy Levels: NAD+ is essential for converting nutrients into cellular energy (ATP), helping to combat fatigue and improve overall vitality.
Enhanced Cellular Repair: NAD+ supports DNA repair and maintenance, promoting cellular health and reducing the effects of aging.
Improved Cognitive Function: Higher NAD+ levels can enhance brain health, improving memory, focus, and cognitive performance.
Metabolic Support: NAD+ plays a key role in regulating metabolism, aiding in weight management and metabolic health.
Anti-Aging Properties: By supporting cellular health and reducing oxidative stress, NAD+ can help slow down the aging process, promoting a youthful appearance and vitality.
Top 10 Reasons NAD+ is Helpful for Women
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell of your body, playing a crucial role in energy production, DNA repair, and overall cellular health. For women in their 40s, taking NAD+ supplements can offer numerous benefits that support longevity and overall well-being. Here are my top 10 reasons why NAD+ is particularly helpful for women in this age group:
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Boosts Cellular Energy: NAD+ is essential for converting nutrients into energy at the cellular level. As we age, our NAD+ levels decline, leading to fatigue and reduced energy. Supplementing with NAD+ can help restore energy levels, making it easier to stay active and engaged in daily life.
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Supports Healthy Aging: NAD+ plays a key role in maintaining the health and function of your cells. By boosting NAD+ levels, you can help slow down the aging process at a cellular level, supporting youthful skin, hair, and overall vitality.
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Enhances DNA Repair: NAD+ is crucial for the repair of damaged DNA, which accumulates as we age and can lead to various age-related diseases. By improving DNA repair, NAD+ helps protect against the development of chronic conditions.
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Improves Cognitive Function: NAD+ supports brain health by enhancing mitochondrial function and reducing oxidative stress. This can improve memory, focus, and cognitive clarity, helping to combat the "brain fog" that many women experience in their 40s.
Supports Metabolism: NAD+ is involved in metabolic processes, including the regulation of blood sugar and fat metabolism. By optimizing these processes, NAD+ can support weight management and reduce the risk of metabolic syndrome.
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Enhances Muscle Health: As women age, maintaining muscle mass and strength becomes more challenging. NAD+ supports muscle function and recovery, helping to preserve muscle mass and reduce the risk of age-related muscle loss.
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Promotes Heart Health: NAD+ is important for maintaining healthy blood vessels and supporting cardiovascular function. By enhancing vascular health, NAD+ can reduce the risk of heart disease, which becomes more prevalent as women age.
Supports Immune Function: NAD+ plays a role in regulating immune responses and reducing inflammation. By boosting NAD+ levels, you can help strengthen your immune system and protect against age-related immune decline.
Balances Hormones: NAD+ is involved in the production and regulation of hormones, including those related to stress, metabolism, and reproduction. By supporting hormonal balance, NAD+ can help alleviate some of the symptoms associated with perimenopause and menopause.
Improves Skin Health: NAD+ supports the health and function of skin cells, promoting collagen production and reducing oxidative stress. This can lead to improved skin elasticity, hydration, and a reduction in the appearance of fine lines and wrinkles.
